These kinds of therapies may cause month-long waits before you start the CAR T therapy process. You may need treatment to become healthy enough to participate in CAR T therapy. Timing of your first appointment and screening tests may vary based on the center’s availability and the health care provider’s schedule. Additional screening tests may be broken into multiple appointments during your first visit. Screening Testsĭuring your first appointment with the CAR T team, you will have screening tests to see if this is a good treatment option for you. The treatment team will do some screening tests to make sure you are eligible and healthy enough to go through the treatment. This appointment will also help the cancer center decide if CAR T is right for you. Your first appointment allows you to learn more about the cancer center’s CAR T program. If you seek a second opinion at a cancer center, you may learn of CAR T that way. Your primary oncologist refers you to a CAR T program to discuss an FDA-approved CAR T therapy or a clinical trial. CAR T cells bind to cancer cells and kill them – Once the CAR T cells are in your bloodstream, they attack the cancer cells.This is done to destroy regular T cells and give the CAR T cells more room to operate. You may get a brief course of chemotherapy (referred to as conditioning chemotherapy) before getting the CAR T infusion. CAR T cells are infused into the patient – Once the CAR T cells are ready, they are infused back into your bloodstream.Millions of CAR T cells are grown – The new CAR T cells continue to grow in the lab until there is enough for your treatment.CAR T cells are made in the lab – CAR proteins, which act like cancer-cell tracking devices, are then added to your T cells.
The T cells may be frozen and kept in a special temperature-controlled storage unit until you are ready to receive treatment. Blood is removed from the patient to get the T cells – T cells are collected from your bloodstream in a procedure called apheresis.Here’s how the CAR T cell therapy process works: With the new CAR protein, these T cells have been described as bionic. CAR T cells harness the power of a patient’s immune system against the cancer. The altered T cells are then returned to the patient’s body to go to work. CAR T cell therapy removes some of a patient’s T cells and alters them to make them better able to fight cancer.
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